PRP099: Using Artificial Intelligence for Diagnosis of Dementia: A Systematic Scoping Review

Lily Puterman-Salzman; Jory Katz; Samira Rahimi, PhD, Eng; Narges Armanfard; Vladimir Khanassov, MD, MSc; Roland Grad, MD, CCFP, FCFP; Isabelle Vedel, MD, PhD; Genevieve Gore, MLIS; Howard Bergman, MDCM; Negar Ghourchian, PhD

Abstract

Context: Dementia is a neurodegenerative disease resulting in the loss of cognitive and psychological functions such as memory loss, confusion and personality changes. It is an extremely difficult diagnosis not only for the patient, but also for their loved ones and care providers. With the increasingly aging population, it is important to timely diagnose dementia. Artificial intelligence (AI) may help in early diagnoses and screening of dementia, however, little is known in this area.
Objective: To identify and evaluate AI interventions that advance the diagnosis or improve the understanding of the prognosis of dementia.
Study design: A scoping review was conducted using the Joanna Briggs Institute framework, and enhanced methodological framework for scoping reviews by Levac et al. The PRISMA-Sc guidelines for scoping reviews were used for development of the protocol and reporting of the review.
Dataset: An information specialist performed a comprehensive search from September 21st 2020 until June 2021 on six databases (i.e., Cochrane Library, MEDLINE, EMBASE, EBSCOhost, Web of Science, CINAHL, and IEEE Xplore). AI interventions, which were implemented or tested in health care settings, were included. The reference lists of included studies were screened. Articles in the English language only were included.
Population studied: Patients with dementia and other neurodegenerative diseases (Alzheimer’s disease, Pick’s Disease, Lewy body Disease, Mild Cognitive Impairment, frontotemporal disorders and vascular dementia) and their care providers were included. Studies were excluded if they focused on diagnosing Parkinsons or Huntington’s disease.
Outcome measures: Any outcome related to patients (e.g., health related and psychological related outcomes), health care providers (e.g., health care provider acceptance, health care provider satisfaction) and the health care system (e.g., direct and indirect health costs, use of health system services, any other health system performance indicator).
Results: After removing duplicates, 2,632 articles were identified. Two independent reviewers conducted title and abstract screening (level 1) and full text screening (level 2). 839 articles were included. The authors categorized the included papers into 6 categories (brain scans, senses, sensors tracking movement, clinical data, biomarkers, and hybrid). This is an ongoing review and the data extraction step is in progress. Preliminary results will be presented.
Leave a Comment
Diane Harper
harperdi@med.umich.edu 11/21/2021

scoping reviews always ground you in the current study designs and outcomes - so that you can improve on the study designs and define measurable outcomes that are clinically meaningful. Thank you for brining this to NAPCRG.

Jack Westfall
jwestfall@aafp.org 11/22/2021

This is a very important topic and research study. Great to see more AI work at NAPCRG. Nice work. Thanks

Pierre Pluye
11/22/2021

Very impresssive, congratulations!

Jaky Kueper
jkueper@uwo.ca 11/22/2021

Nice work. What is your definition of a "hybrid model"? Hybrid in terms of the algorithm specifications and/or the data sources?

Social Media

Address

NAPCRG
11400 Tomahawk Creek Parkway
Leawood, KS 66211
800.274.7928
Email: napcrgoffice@napcrg.org